WebCisplatin is a platinum chemotherapeutic used in a variety of malignancies. The antineoplastic activity occurs from DNA cross-links and adducts, in addition to the generation of superoxide radicals. Nephrotoxicity is the most well-known and potentially most clinically significant toxicity. Unfortunately, the mechanism for cisplatin ... WebApr 3, 2024 · The researchers explained that cisplatin and other platinum-based chemotherapeutic agents are the most common types of agents used in chemotherapy for solid malignancies, with at least 500,000...
Cisplatin (chemotherapy drug) - treatment and side effects
Webof cisplatin with urine from healthy subjects, except that the proportions are different. The parent compound, cisplatin, is excreted in the urine and accounts for 13% to 17% of the dose excreted within one hour after administration of 50 mg/m2. The mean renal clearance of cisplatin exceeds creatinine clearance and is 62 and WebCisplatin NeoCorp 10 mg verschreibungspflichtig Fachinformation Gebrauchsinformation Cisplatin NeoCorp 50 mg im NeoSafe® verschreibungspflichtig Fachinformation … thep351.cc
顺铂 - 维基百科,自由的百科全书
Web顺铂 (英語: Cisplatin , CDDP )是一种含 铂 的抗癌药物,即 顺-二氯二氨合铂 (II) ,棕黄色粉末,属于 细胞周期 非特异性药物 ,对 肉瘤 、 恶性上皮肿瘤 、 淋巴瘤 及生殖细胞肿瘤都有治疗功效。 它是第一个合成 铂类抗癌药物 ,结构简单,机理明确,并引发了对铂类药物研究的热潮,包括 卡铂 、 奥沙利铂 、 奈达铂 及 赛特铂 等。 目录 1 历史 2 作用机理 … WebCisplatin is administered to cancer patients intravenously as a sterile saline solution (that is, containing salt—specifically, sodium chloride). Once cisplatin is in the bloodstream, it remains intact due the relatively high concentration of chloride ions (~100 mM). WebDec 16, 2024 · Cisplatin (CDDP; cis-dichlorodiammine platinum [II]) is a non-specific drug of the cell cycle with strong cytotoxicity and broad-spectrum antitumor effects; it is widely used in urogenital system tumors, malignant lymphoma, breast cancer, head and neck cancer, non-small cell lung cancer, etc. ( 1 – 3) Cisplatin-induced nephrotoxicity is … thep354